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Educational Strategies to Prevent
Prehospital Delay in Patients at High
Risk for Acute Myocardial Infarction

Suzanne K. White, MN, RN, FAAN, FCCM, CNAA
Vice President, Cardiovascular Services/Clinical Affairs
Saint Joseph's Hospital of Atlanta
Atlanta, GA



Quick Overview
  • Acute Myocardial Infarction
  • Education Regarding Symptoms
  • Actions Taken if Symptoms Occur
  • Patient Advisory Form
  • National Heart Atttack Alert Program Coordinating Committee...
  • Patient Representatives
  • NHLBI Staff
  • Support Contract
  • Many effective therapies are now available for patients with acute cardiac ischemia, acute myocardial infarction (AMI), potentially fatal arrhythmias, and cardiogenic shock if they seek and receive care expeditiously. However, delays in accessing and receiving care are a continuing problem, threatening the effectiveness of available treatments. Patients with previously diagnosed coronary heart disease (CHD), including a previous AMI, have the same or greater delay times as those without prior AMI or CHD. Because of the high-risk status of these patients, combined with the problem of delay in seeking care, a Working Group of the National Heart Attack Alert Program (NHAAP), National Heart, Lung, and Blood Institute, of the National Institutes of Health advises physicians and other healthcare providers of their important role in reducing treatment delay in these patients. The Working Group recommends that primary care clinicians in the office and in inpatient settings provide these patients and their family members or significant others contingency counseling about actions to take in response to symptoms of an AMI/acute cardiac ischemia.

    Ideally, education regarding the symptoms and signs of AMI and the need to seek treatment promptly should be directed at all individuals and is a long-term goal of the NHAAP. However, in order to focus resources on individuals who might derive the greatest potential benefit, educational and counseling interventions should be aimed at reducing patient delay for those individuals who are at high risk for a future AMI. Based on health interviews conducted in 1992, approximately 7 million Americans have CHD, about 3 million have cerebrovascular disease, and about 2 million have peripheral vascular disease. (1) Patients with established CHD, clinical atherosclerotic disease of the aorta or peripheral arteries, or clinical cerebrovascular disease are at high risk for subsequent AMI or CHD death. (2-4) The risk for subsequent AMI and death in patients with established CHD (or other atherosclerotic disease) is fivefold to sevenfold higher than for the general population. (2) It is particularly important to focus within this high-risk patient group on women, African Americans, and the elderly; these populations have longer reported delays in seeking care in response to AMI symptoms.

    Education should be targeted at patients with established CHD or clinical atherosclerotic disease, including their family members/significant others. Patients with established CHD include those with a history of AMI, angina, coronary artery bypass surgery, or angioplasty. In addition, patients with previously diagnosed peripheral arterial disease (eg, patients with claudication or an abdominal aortic aneurysm) should be targeted. Substantial carotid atherosclerosis is documented by cerebral symptoms (eg, patients with transient ischemic attacks or stroke) and demonstration of significant atherosclerosis on ultrasound or angiogram. (5)

    The content of the recommended educational message includes three essential components: information, emotional issues, and social factors. Patients should be given information about the typical symptoms of AMI and the action steps to take if they experience any of those symptoms. Although the presentation of AMI can be atypical, (6,7) the majority of patients will present with chest pain/discomfort, left arm pain/heaviness, shortness of breath, or a feeling of dread. (8) The differences in presentation profiles, if any, between patients with a CHD history and those presenting for the first time are not well delineated.

    Providers should keep in mind that presenting symptoms of AMI in the elderly may be vague. Older patients more often have a history of hypertension, congestive heart failure, and MI, as well as longer delay times, than younger patients. Among 1,848 patients more than 65 years of age from the Myocardial Infarction Triage and Intervention (MITI) trial, a relatively high proportion of these elderly individuals had no chest pain when first evaluated in the hospital, and fewer elderly patients had ST elevation on the initial electrocardiogram (ECG). (9)

    Clark et al (10) found that minority patients have lower levels of symptom recognition and belief in treatability. According to Raczynski et al, (11) African-American patients admitted for CHD report fewer painful symptoms and are more likely to attribute symptoms to noncardiac origins (eg, gastrointestinal tract).

    Since many patients believe that an AMI is accompanied by sudden, crushing chest pain and unconsciousness, (12) patients should be told that the symptoms may come on gradually or may be intermittent. The educational message should be adapted to an individual patient's history of symptom presentation; for example, the physician can emphasize jaw discomfort if this symptom occurred in the past as part of the patient's ischemic presentation. However, all of the more frequent presenting symptoms should be addressed since a second heart attack may not manifest itself exactly the same way as the first (something patients should also be told, even though this has not been well studied).

    Patients must be clear about the actions they should take if AMI symptoms occur. These behaviors include taking nitroglycerin (if prescribed), taking aspirin, and calling the emergency medical services (EMS). Advice about medications should be tailored to the needs of individual patients. The guideline for the use of nitrates for anginal pain published in the Clinical Practice Guideline, Unstable Angina: Diagnosis and Management, by the Agency for Health Care Policy and Research Guideline Panel (13) appears sound. Patients are directed to take one nitroglycerin tablet as soon as they feel discomfort, take a second tablet if the discomfort does not go away in 5 minutes, and take a third tablet after 5 more minutes if symptoms persist. If the medication does not relieve the discomfort in 15 minutes, they should go to the hospital immediately by activating EMS.

    Quick Overview
  • Acute Myocardial Infarction
  • Education Regarding Symptoms
  • Actions Taken if Symptoms Occur
  • Patient Advisory Form
  • National Heart Atttack Alert Program Coordinating Committee...
  • Patient Representatives
  • NHLBI Staff
  • Support Contract

  • Because of aspirin's demonstrated benefit in the case of an acute ischemic event, (14) patients should additionally be advised to chew an adult-strength (325 mg), noncoated aspirin tablet as part of their emergency action plan.

    Activation of EMS shortens delay for almost all patients with suspected AMI (15); therefore, high-risk patients and their families should be told to call 9-1-1 or their seven-digit emergency number when a patient has symptoms suggestive of AMI. If a patient lives in a rural area or is a long distance from the nearest hospital, the healthcare provider should discuss the appropriateness and merits of alternative plans. Having a family member or friend drive is not recommended because the person driving the patient cannot render any patient care and usually cannot communicate with the hospital while en route. Arrival at the emergency department (ED)/trauma center by private vehicle has been shown to delay triage and assessment of trauma patients compared with patients conveyed by EMS. (16) For the AMI patient, prehospital identification by history or ECG has been shown to decrease time to treatment in the ED. (17,18)

    A sample form for presenting patient information is presented in Figure 1.


    Figure 1

    Patient Advisory Form



    It can be individualized by physicians and other healthcare providers to include any unusual symptoms a patient may experience suggesting an evolving AMI, instructions for any special medications such as nitrates, aspirin, or others (eg, beta blockers) that the patient may need, the EMS phone number in the community, and the location of the hospital with 24-hour ED service closest to the patient's home and work. Physicians and other healthcare providers can suggest that patients keep the form on their refrigerators or with their other emergency numbers, as well as keep a copy at work. The selected message regarding symptom constellation and recommended action steps should also be recorded in the patient's medical record so it can be reinforced by other healthcare providers in the setting. All instructions should be entered in the patient's record so other members of the healthcare team can reinforce them during future visits.

    Counseling should address the emotional aspects (eg, fear and denial) that patients and those around them may experience, as well as barriers that may be associated with the healthcare delivery system. Because the majority of patients consult a family member or significant other about their symptoms, (19,20) the latter should be included in all education and counseling interactions and have a good understanding of the nature of AMI symptoms and the importance of calling EMS quickly. Assistance from other healthcare providers (eg, nurses) should be solicited to initiate, reinforce, and supplement the counseling. A Patient Advisory Form is offered as an aid to providers in counseling their high-risk patients about these issues. Other materials and aids should be considered as well. Physicians' offices and clinics should devise a system to triage patients rapidly when they call or walk in seeking advice for possible AMI symptoms. Further research is needed to learn more about effective counseling strategies, symptom manifestation in high-risk groups, including women and minorities, and healthcare delivery systems that enhance access to timely care for CHD patients.


    Quick Overview
  • Acute Myocardial Infarction
  • Education Regarding Symptoms
  • Actions Taken if Symptoms Occur
  • Patient Advisory Form
  • National Heart Atttack Alert Program Coordinating Committee...
  • Patient Representatives
  • NHLBI Staff
  • Support Contract

  • National Heart Attack Alert Program Coordinating Committee
    Working Group on Educational Strategies To Prevent Prehospital
    Delay in Patients at High Risk for Acute Myocardial Infarction

    Kathleen Dracup, RN, DNSc (Chair)
    Professor and LW Hassenplug Chair of Nursing
    School of Nursing
    University of California at Los Angeles
    Los Angeles, CA

    Angelo A. Alonzo, PhD
    Associate Professor of Sociology
    The Ohio State University
    Columbus, OH

    James M. Atkins, MD, FACC
    Medical Director, Dallas Emergency Medical Services
    Professor of Medicine
    Department of Internal Medicine
    University of Texas Southwestern Medical
    Center at Dallas
    Dallas, TX

    Nancy M. Bennett, MD, MS
    Assistant Professor of Medicine
    Assistant Professor of Community and Preventive Medicine
    University of Rochester School of Medicine and Dentistry
    Deputy Health Director
    Monroe County Health Department
    Rochester, NY

    Allan Braslow, PhD
    President
    Braslow and Associates
    Alexandria, VA

    Luther Clark, MD
    Director of Preventive Cardiology
    Associate Professor of Clinical Medicine
    Department of Medicine
    State University of New York Health Science Center
    Brooklyn, NY

    Mickey Eisenberg, MD, PhD
    Professor of Medicine
    University of Washington
    Emergency Medical Services
    University of Washington Medical Center
    Seattle, WA

    Keith Copelin Ferdinand, MD, FACC
    Medical Director
    Heartbeats Life Center of New Orleans
    Associate Professor, Clinical Pharmacology
    College of Pharmacy
    Xavier University of New Orleans
    New Orleans, LA

    Robert Frye, MD, FACC
    Chair, Internal Medicine
    Professor of Medicine
    Cardiovascular Consultant
    Mayo Clinic
    Rochester, MN

    Lee Green, MD, MPH
    Assistant Professor
    Department of Family Practice
    University of Michigan Medical School
    Ann Arbor, MI

    Martha Hill, PhD, RN
    Associate Professor
    School of Nursing
    Johns Hopkins University
    Baltimore, MD

    J. Ward Kennedy, MD
    Professor of Medicine
    University of Washington
    Director, Division of Cardiology
    University Hospital
    Seattle, WA

    Eva Kline-Rogers, MS, RN
    Clinical Nurse Specialist
    Cardiology Department
    University of Michigan Medical Center
    Ann Arbor, MI

    Debra K. Moser, DNSc, RN
    Assistant Professor of Nursing
    College of Nursing
    Ohio State University
    Columbus, OH

    Joseph P. Ornato, MD, FACC
    Professor of Internal Medicine (Cardiology)
    Director of Research
    Department of Emergency Medicine
    Virginia Commonwealth University/Medical College of Virginia
    Richmond, VA

    Bertram Pitt, MD
    Professor of Internal Medicine
    Division of Cardiology
    University of Michigan Hospital
    Ann Arbor, MI

    Jane D. Scott, ScD, MSN
    Health Scientist Administrator
    Center for Medical Effectiveness Research
    Agency for Health Care Policy and Research
    Rockville, MD

    Harry P. Selker, MD, MSPH
    Chief, Division of Clinical Care Research
    Director, Center for Cardiovascular Health Services Research
    New England Medical Center
    Associate Professor of Medicine
    Tufts University School of Medicine
    Boston, MA

    Sharon Silva, PhD
    Evaluation Associate
    Public Policy and Planning
    American Red Cross National Headquarters
    Washington, DC

    William Thies, PhD
    Director
    Emergency Cardiac Care Programs
    American Heart Association
    Dallas, TX

    W. Douglas Weaver, MD
    Professor of Medicine
    Director, Cardiovascular Critical Care
    University of Washington
    Seattle, WA

    Nanette K. Wenger, MD
    Professor of Medicine (Cardiology)
    Emory University School of Medicine
    Director, Cardiac Clinics
    Grady Memorial Hospital
    Atlanta, GA

    Suzanne K. White, MN, RN, FAAN, FCCM, CNAA
    Vice President, Cardiovascular Services/Clinical Affairs
    St. Joseph's Hospital of Atlanta
    Atlanta, GA

    Quick Overview
  • Acute Myocardial Infarction
  • Education Regarding Symptoms
  • Actions Taken if Symptoms Occur
  • Patient Advisory Form
  • National Heart Atttack Alert Program Coordinating Committee...
  • Patient Representatives
  • NHLBI Staff
  • Support Contract

  • Patient Representatives

    Alan Jung, DDS
    Baltimore, MD
    Ms. Jane Lynn
    Severna Park, MD

    NHLBI Staff:

    Patrice Desvigne-Nickens, MD
    Director, Heart Research Program
    Division of Heart and Vascular Diseases
    National Heart, Lung, and Blood Institute
    National Institutes of Health
    Bethesda, MD

    Mary M. Hand, MSPH, RN
    Coordinator, National Heart Attack Alert Program
    Office of Prevention, Education, and Control
    National Heart, Lung, and Blood Institute
    National Institutes of Health
    Bethesda, MD

    Michael Horan, MD, ScM
    Director
    Division of Heart and Vascular Diseases
    National Heart, Lung, and Blood Institute
    National Institutes of Health
    Bethesda, MD

    Denise Simons-Morton, MD, PhD
    Medical Officer
    Division of Epidemiology and Clinical Applications
    National Heart, Lung, and Blood Institute
    National Institutes of Health
    Bethesda, MD

    George Sopko, MD
    Medical Officer
    Health Scientist Administrator
    Division of Heart and Vascular Diseases
    National Heart, Lung, and Blood Institute
    National Institutes of Health
    Bethesda, MD

    Support Contract

    John C. Bradley, MS
    R.O.W. Sciences, Inc.
    Rockville, MD

    Susan Shero, RN, MS
    R.O.W. Sciences, Inc.
    Rockville, MD

    Acknowledgement: Mary Pat Larsen, King County Department of Emergency Medical Services, Seattle, WA, for statistical support.

    References  


     1. National Heart, Lung, and Blood Institute. Morbidity and Mortality. Chartbook on Cardiovascular, Lung, and Blood Diseases. Public Health Service, National Institutes of Health, National Heart, Lung, and Blood Institute. May 1994.

     2. Criqui MH, Langer RD, Fronek A, et al. Mortality over a period of 10 years in patients with peripheral arterial disease. N Engl J Med. 1992;326:381-386.

     3. Pekkanen J, Linn S, Heiss G, et al. Ten-year mortality from cardiovascular disease in relation to cholesterol level among men with and without preexisting cardiovascular disease. N Engl J Med. 1990;322:1700-1707.

     4. Salonen JT, Salonen R. Ultrasonographically assessed carotid morphology and the risk of coronary heart disease. Arterioscler Thromb. 1991;11:1245-1249.

     5. National Cholesterol Education Program. Second Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II). National Institutes of Health. National Heart, Lung, and Blood Institute. NIH Publication No. 93-3095. September 1993.

     6. Margolis JR, Kannel WS, Feinleib M, et al. Clinical features of unrecognized myocardial infarction - silent and symptomatic. Eighteen-year follow-up: the Framingham study. Am J Cardiol. 1973;32:1-7.

     7. Uretsky BF, Farquhar DS, Berezin AF, et al. Symptomatic myocardial infarction without chest pain: prevalence and clinical course. Am J Cardiol. 1977;40:498-503.

     8. Gillum RF, Fortmann SP, Prineas RJ, et al. International diagnostic criteria for acute myocardial infarction and stroke. Am Heart J. 1984;108:150-158.

     9. Weaver WD, Litwin PE, Martin JS, et al. (MITI Project Group). Effect of age on use of thrombolytic therapy and mortality in acute myocardial infarction. J Am Coll Cardiol. 1991;18:657-662.

    10. Clark LT, Bellam SV, Shah AH, et al. Analysis of prehospital delay among inner-city patients with symptoms of myocardial infarction: implications for therapeutic intervention. J Natl Med Assoc. 1992;84:931-937.

    11. Raczynski JM, Taylor H, Cutter G, et al. Diagnoses, symptoms, and attribution of symptoms among black and white inpatients admitted for coronary heart disease. Am J Public Health. 1994;84:951-956.

    12. Johnson JA, King KB. The influence of expectations about symptoms on delay in seeking treatment during myocardial infarction. Am J Crit Care. 1995;4:29-35.

    13. Braunwald E, Mark DB, Jones RH, et al. Unstable Angina: Diagnosis and Management. Clinical Practice Guideline Number 10. AHCPR Publication No. 94-0602. Rockville, MD: Agency for Health Care Policy and Research and the National Heart, Lung, and Blood Institute, Public Health Service, U.S. Department of Health and Human Services. March 1994.

    14. Second International Study of Infarct Survival (ISIS-2) Steering Committee. Intravenous streptokinase given within 0-4 hours of onset of myocardial infarction reduced mortality in ISIS-2. Lancet. 1987;1:502. Letter.

    15. Weaver WD, Kennedy JW. Myocardial infarction - thrombolytic therapy in the prehospital setting. In: Fuster V, Verstraete M, eds. Thrombosis in Cardiovascular Disorders. Philadelphia, PA: WB Saunders Co; 1992:275-287.

    16. Hammond J, Gomez GA, Fine E, et al. The non-use of 9-1-1. Private transport of trauma patients to a trauma center. Prehospital Disaster Med. 1993;8:35-38.

    17. Kereiakes DJ, Weaver D, Anderson JL, et al. Time delays in the diagnosis and treatment of acute myocardial infarction: a tale of eight cities. Report from the Pre-hospital Study Group and the Cincinnati Heart Project. Am Heart J. 1990;120:773-780.

    18. Weaver WD, Cerqueira M, Hallstrom AP, et al, for the Myocardial Infarction Triage and Intervention Project Group. Prehospital-initiated vs hospital-initiated thrombolytic therapy. The Myocardial Infarction Triage and Intervention trial. JAMA. 1993;270:1211-1216.

    19. Alonzo AA. The impact of the family and lay others on care-seeking during life-threatening episodes of suspected coronary artery disease. Soc Sci Med. 1986;22:1297-1311.

    20. Reilly A, Dracup K, Dattolo J. Factors influencing prehospital delay in patients experiencing chest pain. Am J Crit Care. 1994;3:300-306.

    Return to Index of Articles for Clinician; Volume 14.4


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