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Nuclear Cardiology

Title: The feasibility of having rest cardiolyte (sestamibi) available 24 hours a day, 7 days a week for use in chest pain patients with low probability of having ischemic heart disease.
 
  The current status of using rest sestamibi in the risk stratification of chest pain patients with low probability of having ischemic heart disease was recently discussed in a panel session with Dr. Ethan Spiegler at St. Agnes HealthCare, Baltimore, Maryland, James Tatum, MD Medical College of Virginia (VCU) and Stephen Stowers, MD St. Luke's Hospital in Jacksonville, Florida. (1) The benefit of having sestamibi available 24 hours a day, 7 days a week was encouraged and made easy with the following comments from Dr. Spiegler.
       "The patient is hopefully injected during the chest pain symptoms. After a call to Nuclear Medicine, it usually takes 10 minutes for the dose to be given. Sestamibi is useful because it basically works like a microsphere. It imbeds into the heart muscle according to blood flow so that scanning does not have to take place immediately. The scanning process with the new kind of cameras and computer software available takes approximately 15 minutes so that the patient spends a short time in the scanner. The images can be gated as they are acquired. The gated images provide the ability to look at each tomographic slice of the heart beating and allow information on not only the perfusion, but also wall motion, wall thickening, and ejection fraction.
       With this single test a lot of patient evaluation information is made available. In high volume institutions, an in-house technologist is available 24 hours a day, 7 days a week such as takes place at the Medical College of Virginia (VCU). In our own institution (St. Agnes HealthCare) the technologist is available until 10 pm. After that, the emergency physician has been taught and licensed to give the dose. Since scanning does not have to take place immediately, in most cases after 10 pm it can be done early the next morning. At any time the data can be relayed from the computer at the hospital via a modem to the physician at home for the data to be interpreted rapidly. To make this program acceptable one must make sure that there is a mechanism in place not to pay for doses of radio pharmaceuticals that are not injected. Presently at St. Agnes HealthCare, if the sestamibi dose is not used then there is no charge for it. Similar arrangements can be made with local radio pharmacies which makes good financial sense".
  In summary the availability of sestamibi for early risk stratification presenting in the emergency department is feasible 24 hours a day for 7 days a week with minimal cost utilizing the strategy outlined above.
 

 

Raymond D. Bahr, MD, FACP, FACC
Medical Director
The Paul Dudley White Coronary Care System
St. Agnes HealthCare



References:

(1)    Spiegler EJ. Implementation of an acute myocardial perfusion imaging program for patients with chest pain and nondiagnostic electrocardiogram: the St. Agnes experience. The Strategy of Chest Pain Units (in Emergency Departments) in the War Against Heart Attacks. Proceedings from the First Maryland Chest Pain Center Research Conference. Maryland Medical J 1997 46:10 33-35. (Suppl.).
   
(2)    Spiegler EJ, Stowers S, Tatum J. Current status of sestamibi in the risk stratification of chest pain patients: a panel discussion. The Strategy of Chest Pain Units (in Emergency Departments) in the War Against Heart Attacks. Proceedings from the First Maryland Chest Pain Center Research Conference. Maryland Medical J 1997 46:10 1-4. (Suppl.).






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